IBA57 Polyclonal Antibody

Reddot Biotech

IBA57 Polyclonal Antibody

5

0.9 mg/ml

IBA57

iron-sulfur cluster assembly factor IBA57

C1orf69; IBA57 homolog, iron-sulfur cluster assembly; IBA57, iron-sulfur cluster assembly homolog; iron-sulfur cluster assembly factor for biotin synthase- and aconitase-like mitochondrial proteins, with a mass of 57kDa; MMDS3; putative transferase C1orf69, mitochondrial; putative transferase CAF17, mitochondrial; SPG74

The protein encoded by this gene localizes to the mitochondrion and is part of the iron-sulfur cluster assembly pathway. The encoded protein functions late in the biosynthesis of mitochondrial 4Fe-4S proteins. Defects in this gene have been associated with autosomal recessive spastic paraplegia-74 and with multiple mitochondrial dysfunctions syndrome-3. Two transcript variants encoding different isoforms have been found for this gene. The smaller isoform is not likely to be localized to the mitochondrion since it lacks the amino-terminal transit peptide.

-20°C

12352203