ICA-105665 [2694728-63-5]

TargetMol Chemicals

ICA-105665 [2694728-63-5]

10

Chemical

Research Use Only

ICA-105665

C19H15F2N3O2

355.34

ICA-105665 (PF-04895162) is a potent and orally active opener of neuronal Kv7.2/7.3 and Kv7.3/7.5 potassium channels. ICA-105665 had low cytotoxic potential in human hepatocytes but inhibited liver mitochondrial function and bile salt export protein (BSEP) transport (IC50 of 311 microM). ICA-105665 can penetrate the central nervous system (CNS) and has antiseizure effects [1][2][3][4].

3 years

N(C(CC1=CC=C(F)C=C1)=O)N2C(=NC=3C(C2=O)=CC=C(F)C3)C4CC4

-20°C

12352200