ICA-105665

MedChem Express

ICA-105665

10

Research Use Only

99.85

C19H15F2N3O2

355.34

ICA-105665 (PF-04895162) is a potent and orally active neuronal Kv7.2/7.3 and Kv7.3/7.5 potassium channels opener. ICA-105665 inhibits liver mitochondrial function and bile salt export protein (BSEP) transport ( IC 50 of 311 microM). ICA-105665 can penetrate the blood-brain barrier and has antiseizure effects [1] [2] [3] [4] .

O=C(NN1C(C2CC2)=NC3=C(C=CC(F)=C3)C1=O)CC4=CC=C(F)C=C4

-20°C,2°C to 8°C

12352200