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ICA-27243

T15545
TargetMol Chemicals
CAS Number325457-89-4
Product group Chemicals
Molecular Weight268.65
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    ICA-27243
  • Delivery Days Customer
    4
  • CAS Number
    325457-89-4
  • Category Supplier
    Chemical
  • Chemical Name
    ICA-27243
  • Molecular Formula
    C12H7ClF2N2O
  • Molecular Weight
    268.65
  • Scientific Description
    ICA-27243 is less effective at activating KCNQ4 and KCNQ3/Q5. ICA-27243 is a potent and orally active KCNQ2/Q3 potassium channel opener (EC50: 0.38 uM). ICA-27243 also has antiepileptic and anticonvulsant effects.
  • Shelf life instruction
    3 years
  • SMILES
    C(NC=1C=CC(Cl)=NC1)(=O)C2=CC(F)=C(F)C=C2
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Wickenden AD, et al. N-(6-chloro-pyridin-3-yl)-3,4-difluoro-benzamide (ICA-27243): a novel, selective KCNQ2/Q3 potassium channel activator. Mol Pharmacol. 2008 Mar;73(3):977-86.
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