Icam5 Polyclonal Antibody

Reddot Biotech

Icam5 Polyclonal Antibody

5

Western Blot

Research Use Only

1 mg/ml

Unconjugated

Icam5

intercellular adhesion molecule 5, telencephalin

CD50; Ica; Icam3; ICAM-3; ICAM-5; intercellular adhesion molecule 3; intercellular adhesion molecule 5; T; telencephalin; Tl; Tlcn; TLN

Rabbit

IgG

ICAM-5, also known as telencephalin, is a type I integral membrane glycoprotein of the immunoglobulin superfamily. It is specifically expressed in the postnatal excitatory neuronal cell bodies, dendritic shafts, and dendritic filopodia of the telencephalon. ICAM-5 functions in both the immune and nervous systems. ICAM-5 strongly stimulates neurite outgrowth. It is cleaved by matrix metalloproteases upon activation of glutamate receptors or degraded through endocytosis resulting in increased spine maturation. The cleaved soluble fragment of ICAM-5 is immunosuppressive, which may be important in neuronal inflammatory diseases.

Mouse, Rat

-20°C

12352203