Idetrexed

MedChem Express

Idetrexed [501332-69-0]

10

501332-69-0

Research Use Only

C32H33N5O10

647.63

Idetrexed is a thymidylate synthase inhibitor specifically transported into alpha-folate receptor (alpha-FR)-overexpressing tumors. BGC 945 inhibited thymidylate synthase with a K i of 1.2 nmol/L [1] [2] .

C#CCN(C1=CC=C(C=C1)C(N[C@H](C(O)=O)CCC(N[C@@H](C(O)=O)CCC(O)=O)=O)=O)[C@@H]2C3=CC(C(N=C(N4)CO)=O)=C4C=C3CC2

12352200