IDO1/TDO-IN-4

TargetMol Chemicals

IDO1/TDO-IN-4

14

461424-21-5

Chemical

IDO1/TDO-IN-4

C14H10N4

234.26

IDO1/TDO-IN-4 displays potent inhibition of both IDO1 (IC50 = 3.53 uM) and TDO (IC50 = 1.15 uM) and has an acceptable safety profile and pharmacokinetic properties. IDO1/TDO-IN-4 forms a hydrogen bond with IDO1, and pi pi stacking interaction with TDO. IDO1/TDO-IN-4 can be used in the research of depression and inflammation-induced depression [1].

3 years

C1=2C(C=3C(N1)=CC=CC3)=CC=NC2C4=CN=CN4

-20°

12352200