IDOR-1117-2520 [2737274-49-4]

TargetMol Chemicals

IDOR-1117-2520 [2737274-49-4]

16

Research Use Only

C25H32N4O3

436.55

IDOR-1117-2520 is a highly potent and selective antagonist of CCR6, effectively impeding CCL20-mediated calcium flow with an IC50 of 63 nM and inhibiting beta-arrestin recruitment to human CCR6 with an IC50 of 30 nM in cells expressing recombinant human CCR6. This compound is suitable for researching autoimmune diseases [1].

[C@](O)([C@]1(C)CN(C)C1)(C=2C=C(C=NC2)C=3N=C(C(C)(C)O)ON3)C4=CC=C(C(C)C)C=C4

-20°C

12352200