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IDO/TDO-IN-1

T11623
TargetMol Chemicals
CAS Number2033173-01-0
Product group Chemicals
Molecular Weight413.49
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    IDO/TDO-IN-1
  • Delivery Days Customer
    72
  • CAS Number
    2033173-01-0
  • Category Supplier
    Chemical
  • Chemical Name
    IDO/TDO-IN-1
  • Molecular Formula
    C25H24FN5
  • Molecular Weight
    413.49
  • Scientific Description
    IDO/TDO-IN-1 is an orally active dual indoleamine-2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) inhibitor (IC50s: 9.7 and 47 nM).
  • Shelf life instruction
    3 years
  • SMILES
    FC1=C2[C@@H](N3C(C2=CC=C1)=CN=C3)[C@H]4CCN(CC4)C5=CC=C(C=C5)C6=CN(C)N=C6
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Tu W, et al. Discovery of Imidazoisoindole Derivatives as Highly Potent and Orally Active Indoleamine-2,3-dioxygenase Inhibitors. ACS Med Chem Lett. 2019 Jun 3;10(6):949-953.
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