IFNAR1, Mouse (HEK293, Fc)
HY-P78308
Protein IDP33896
Product group Proteins / Signaling Molecules
Overview
- SupplierMedChem Express
- Product NameIFNAR1, Mouse (HEK293, Fc)
- Delivery Days Customer10
- CertificationResearch Use Only
- Protein IDP33896
- Protein NameInterferon alpha/beta receptor 1
- Scientific DescriptionIFNAR1, one of the subunit of IFN-alpha/beta receptor, is a type I IFN receptor. IFNAR1 forms the heterodimeric receptor with IFNAR2. IFNAR1 mediates IFN-induced STAT signaling by interacting with tyrosine kinase 2 (Tyk2) [1] [2] . Upon activation by these IFNs, IFNAR1 and IFNAR2 undergo a conformational change to promote a cascade of downstream signaling events, including the phosphorylation of Tyk2 and JAK1, STAT1 and STAT2 [3] . IFNAR1 Protein, Mouse (HEK293, Fc) is a recombinant mouse IFNAR1 (E27-T429) with C-terminal hFc tag, which is produced in HEK293 cells.
- UNSPSC12352202