Bio-Connect

IFT57 Polyclonal Antibody

RD81861A
Reddot Biotech
TargetIFT57
Product group Antibodies
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    IFT57 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Concentration
    1 mg/ml
  • Gene ID55081
  • Target name
    IFT57
  • Target description
    intraflagellar transport 57
  • Target synonyms
    dermal papilla-derived protein 8; ESRRBL1; estrogen-related receptor beta like 1; estrogen-related receptor beta-like protein 1; HIP1 protein interactor; HIP1-interacting protein; HIPPI; huntingtin interacting protein-1 interacting protein; intraflagellar transport 57 homolog; intraflagellar transport protein 57 homolog; MHS4R2; OFD18
  • Scientific Description
    Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5-AAAGACATG-3 present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203