IGF1R Polyclonal Antibody

Reddot Biotech

IGF1R Polyclonal Antibody

5

ImmunoFluorescence, ImmunoHistoChemistry

Research Use Only

1 mg/ml

Unconjugated

IGF1R

insulin like growth factor 1 receptor

CD221; IGF-I receptor; IGFIR; IGFR; insulin-like growth factor 1 receptor; JTK13; soluble IGF1R variant 1; soluble IGF1R variant 2

Rabbit

IgG

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Human, Mouse, Rat

-20°C

12352203