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IGF1R/CD221 Protein, Human, Recombinant (His & Avi)

IGF1R/CD221 Protein, Human, Recombinant (His & Avi)

TMPK-00455
TargetMol Chemicals
Molecular Weight105.8 kDa (alpha subunit) and 23 kDa (beta subunit) (predicted). Due to glycosylation, the protein migrates to 110-120 kDa(alpha subunit) and 52-55 kDa(beta subunit) based on Tris-Bis PAGE result.
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    IGF1R/CD221 Protein, Human, Recombinant (His & Avi)
  • Delivery Days Customer
    16
  • Certification
    Research Use Only
  • Molecular Weight
    105.8 kDa (alpha subunit) and 23 kDa (beta subunit) (predicted). Due to glycosylation, the protein migrates to 110-120 kDa(alpha subunit) and 52-55 kDa(beta subunit) based on Tris-Bis PAGE result.
  • Scientific Description
    The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, protease secretion, tumour cell motility and adhesion, and thus can affect the propensity for invasion and metastasis. Therefore, the IGF1R is now an attractive anti-cancer treatment target. IGF1R/CD221 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 105.8 kDa (alpha subunit) and 23 kDa (beta subunit) and the accession number is P08069.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200