IGF2R Polyclonal Antibody

Reddot Biotech

IGF2R Polyclonal Antibody

5

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

0.4 mg/ml

Unconjugated

IGF2R

insulin like growth factor 2 receptor

300 kDa mannose 6-phosphate receptor; cation-independent mannose-6-phosphate receptor; CD222; CI Man-6-P receptor; CI-M6PR; CIMPR; IGF-II receptor; insulin-like growth factor II receptor; M6P/IGF2 receptor; M6P/IGF2R; M6P-R; MPR 300; MPR1; MPR300; MPRI

Rabbit

IgG

This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.

Human, Mouse

-20°C

12352203