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IKK 16 hydrochloride

IKK 16 hydrochloride

T15557
TargetMol Chemicals
CAS Number1186195-62-9
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Product group Chemicals
Molecular Weight520.09
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    IKK 16 hydrochloride
  • Delivery Days Customer
    14
  • CAS Number
    1186195-62-9
  • Category Supplier
    Chemical
  • Chemical Name
    IKK 16 hydrochloride
  • Molecular Formula
    C28H30ClN5OS
  • Molecular Weight
    520.09
  • Scientific Description
    IKK 16 hydrochloride is a selective IKK2, IKK complex, and IKK1 IkappaB kinase (IKK) inhibitor (IC50s: 40 nM, 70 nM and 200 nM, respectively). IKK16 inhibits leucine-rich repeat kinase-2 (LRRK2; IC50: 50 nM).
  • Shelf life instruction
    3 years
  • SMILES
    Cl.O=C(C1=CC=C(C=C1)NC2=NC=CC(=N2)C=3SC=4C=CC=CC4C3)N5CCC(N6CCCC6)CC5
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Hermanson SB, et al. Screening for novel LRRK2 inhibitors using a high-throughput TR-FRET cellular assay for LRRK2 Ser935 phosphorylation. PLoS One. 2012;7(8):e43580.
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