IKK(epsilon)-IN-1 (IKKE-IN-1)

Biorbyt

IKK(epsilon)-IN-1 (IKKE-IN-1) [1292310-49-6]

16

1292310-49-6

Research Use Only

C26H27N5O3

457.5243

IKKepsilon-IN-1 is a potent IKKepsilon inhibitor; inhibit the in-situ iotaKkappa epsilon-mediated phosphorylation of IRF3 with an IC50 value of less than about 100 nM.

O1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])OC1C([H])=C([H])C(C2C([H])=C([H])N=C(N=2)N([H])C2C([H])=C([H])C(=C([H])C=2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C([H])C=1C#N

12352200