IL-1B / IL-1 Beta Protein (Recombinant) (Ala115-Pro267)

LifeSpan BioSciences

IL-1B / IL-1 Beta Protein (Recombinant) (Ala115-Pro267)

23

Research Use Only

>95%

Interleukin-1 beta (rpIL-1Beta) is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. IL-1a and IL-1Beta are structurally related polypeptides that share approximately 27% amino acid (aa) identity in porcine. While IL-1a and IL-1Beta are regulated independently, they bind to the same receptor and exert identical biological effects. IL-1Beta stimulates thymocyte proliferation by inducing il-2 release, b-cell maturation and proliferation, and fibroblast growth factor activity.Recombinant Porcine IL-1Beta produced in E. coli is a single non-glycosylated polypeptide chain containing 154 amino acids. A fully biologically active molecule, rpIL-1Beta has a molecular mass of 17.7 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques.

2°C to 8°C,-20°C,-80°C

12352202