IL-1 Receptor Type I (human):Fc (human) (rec.)

AdipoGen Life Sciences

IL-1R1 (human):Fc (human) (rec.)

10

Research Use Only

1 mg/ml

>95%

Interleukin-1 receptor type 1

IL-1RI is the receptor for interleukin-1alpha (IL-1A), beta (IL-1B) and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappaB. Signaling involves formation of a ternary complex containing IL1RAP, leading the activation of TOLLIP, MYD88 and IRAK1 or IRAK2. - Protein. Human IL-1RI (interleukin-1 receptor type I) (aa 21-336) is fused at the C-terminus to the Fc portion of human IgG1. Source: HEK 293 cells. Endotoxin content: <0.1EU/microg purified protein (LAL test; Lonza). Lyophilized. Contains PBS. Binds to human IL-1beta. Purity: >95% (SDS-PAGE). IL-1RI is the receptor for interleukin-1alpha (IL-1A), beta (IL-1B) and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappaB. Signaling involves formation of a ternary complex containing IL1RAP, leading the activation of TOLLIP, MYD88 and IRAK1 or IRAK2.

-20°C,2°C to 8°C

12352202