IL-36 alpha/IL-1F6, Mouse

MedChem Express

IL-36 alpha/IL-1F6, Mouse (153a.a)

5

Research Use Only

98.00

Interleukin-36 alpha

IL-36 alpha (IL-1F6), a subform of IL-36 family, belongs to IL-1 superfamily. IL-36 alpha mediates inflammatory response. IL-36 alpha binds to IL-36R and activates NF-kappaB and MAPK signaling pathways, but the activation requires N-terminal cleavage by neutrophil granule-derived proteases [1] . IL-36 alpha also binds to IL-1Rrp2 and recruit IL-1RAcP. IL-36 alpha activats the MAPK, Erk1/2 and JNK through IL-36R/IL-1RAcP [2] . IL-36 alpha/IL-1F6 Protein, Mouse is a recombinant mouse IL-36 alpha without any tag, which is produced in E. coli .

-20°C

12352202