![IL-4 / Interleukin 4(IL4/1597), CF640R conjugate, 0.1mg/mL [26628-22-8] IL-4 / Interleukin 4(IL4/1597), CF640R conjugate, 0.1mg/mL [26628-22-8]](https://biotium.com/wp-content/uploads/2021/02/view_image-495.jpeg)
IL-4 / Interleukin 4(IL4/1597), CF640R conjugate, 0.1mg/mL [26628-22-8]
BNC401597
ReactivityBovine, Human, Mouse
Product group Antibodies
TargetIL4
Overview
- SupplierBiotium
- Product NameIL-4 / Interleukin 4(IL4/1597), CF640R conjugate, 0.1mg/mL
- Delivery Days Customer9
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDIL4/1597
- Concentration0.1 mg/ml
- ConjugateOther Conjugate
- Gene ID3565
- Target nameIL4
- Target descriptioninterleukin 4
- Target synonymsB cell growth factor 1; B_cell stimulatory factor 1; BCGF1; BCGF-1; binetrakin; BSF1; BSF-1; IL-4; interleukin 4 variant 2; interleukin-4; lymphocyte stimulatory factor 1; pitrakinra
- HostMouse
- IsotypeIgG2b
- Protein IDP05112
- Protein NameInterleukin-4
- Scientific DescriptionInterleukin-4 (IL-4), also designated B cell stimulatory factor-1, is a glycosylated cytokine secreted by activated T lymphocytes, basophils and mast cells. The secreted IL-4 protein promotes the growth and differentiation of cells that participate in immune defense by favoring such events as the expansion of the Th2 lineage relative to Th1 cells. These T helper cell subsets are defined by their pattern of cytokine secretion: Th1 cells secrete IL-2, TNF, while Th2 cells secrete IL-4, IL-5 and IL-10. Another key immunological function of IL-4 is to induce immunoglobulin class switching. IL-4 has been shown to induce the production of IgE and enhance IgG4 secretion by B cells, but suppress the production of IgM, IgA, IgG1, IgG2 and IgG3. It has been determined that Stat6 is rapidly tyrosine phosphorylated following stimulation of IL-3 or IL-4, but is not detectably phosphorylated following stimulation with IL-2, IL-12 or erythropoietin. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- SourceAnimal
- ReactivityBovine, Human, Mouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203