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IL-4 / Interleukin 4(IL4/1597), CF640R conjugate, 0.1mg/mL [26628-22-8]

IL-4 / Interleukin 4(IL4/1597), CF640R conjugate, 0.1mg/mL [26628-22-8]

BNC401597
Biotium
ReactivityBovine, Human, Mouse
Product group Antibodies
TargetIL4
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Overview

  • Supplier
    Biotium
  • Product Name
    IL-4 / Interleukin 4(IL4/1597), CF640R conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    IL4/1597
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID3565
  • Target name
    IL4
  • Target description
    interleukin 4
  • Target synonyms
    B cell growth factor 1; B_cell stimulatory factor 1; BCGF1; BCGF-1; binetrakin; BSF1; BSF-1; IL-4; interleukin 4 variant 2; interleukin-4; lymphocyte stimulatory factor 1; pitrakinra
  • Host
    Mouse
  • Isotype
    IgG2b
  • Protein IDP05112
  • Protein Name
    Interleukin-4
  • Scientific Description
    Interleukin-4 (IL-4), also designated B cell stimulatory factor-1, is a glycosylated cytokine secreted by activated T lymphocytes, basophils and mast cells. The secreted IL-4 protein promotes the growth and differentiation of cells that participate in immune defense by favoring such events as the expansion of the Th2 lineage relative to Th1 cells. These T helper cell subsets are defined by their pattern of cytokine secretion: Th1 cells secrete IL-2, TNF, while Th2 cells secrete IL-4, IL-5 and IL-10. Another key immunological function of IL-4 is to induce immunoglobulin class switching. IL-4 has been shown to induce the production of IgE and enhance IgG4 secretion by B cells, but suppress the production of IgM, IgA, IgG1, IgG2 and IgG3. It has been determined that Stat6 is rapidly tyrosine phosphorylated following stimulation of IL-3 or IL-4, but is not detectably phosphorylated following stimulation with IL-2, IL-12 or erythropoietin. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203