Dose response curve of IL-6 Responsive Luciferase Reporter HEK293 Cell Line to hIL-6.
IL-6 Responsive Luciferase Reporter HEK293 Cell Line
82235
Product group (Cell) Culture
Overview
- SupplierBPS Bioscience
- Product NameIL-6 Responsive Luciferase Reporter HEK293 Cell Line
- Delivery Days Customer7
- ApplicationsNeutralisation/Blocking
- CertificationResearch Use Only
- Scientific DescriptionIL-6 Responsive Luciferase Reporter HEK293 Cell Line is a HEK293 cell line designed to monitor the IL-6 (interleukin 6)/IL-6 receptor interaction. These cells express endogenous IL-6 receptor (IL-6R and gp130) and were engineered to express firefly luciferase under the control of a STAT response element. This cell line has been validated to respond to human interleukin-6 (IL-6), IL-27, and further functional validation experiments showed that IL-6-induced luciferase activity was decreased by the JAK inhibitor CP 690,550 and by an anti-IL-6R neutralizing antibody.
- Storage InstructionLiquid Nitrogen
- UNSPSC12352207