IL-6R alpha Protein, Human (CHO)

MedChem Express
Protein IDP08887
Product group Proteins / Signaling Molecules
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  • Supplier
    MedChem Express
  • Product Name
    IL-6R alpha Protein, Human (CHO)
  • Delivery Days Customer
  • Protein IDP08887
  • Protein Name
    Interleukin-6 receptor subunit alpha
  • Scientific Description
    IL-6R alpha is a subunit alpha of IL-6 receptors, also shared by other interleukin receptors. IL-6R alpha acts as IL-6 agonist and involves in JAK/STAT, MAPK, and Akt signaling pathway. IL-6R alpha/CD126, Human consists of 468 amino acids (M1-R468) with two fibronectin type-III-like domains contained in the N-terminal part (113-217 a.a, 218-316 a.a), and a soluble form (1-365 a.a). Soluble IL-6R (sIL-6R) binds IL-6 and dimerized gp130 to achieve trans signaling, and exhibits a tissue expression property in some immune systems. IL-6R alpha Protein, Human (L20-P365) is soluble form and expressed by CHO cells with a full length of the sequence of 346 amino acids.
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C