IHC-P analysis of rat kidney tissue using GTX33963 IL10 antibody.
IHC-P analysis of rat kidney tissue using GTX33963 IL10 antibody.
IL10 antibody
GTX33963
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityRat
TargetIL10
Overview
- SupplierGeneTex
- Product NameIL10 antibody
- Delivery Days Customer9
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID3586
- Target nameIL10
- Target descriptioninterleukin 10
- Target synonymsCSIF; cytokine synthesis inhibitory factor; GVHDS; IL-10; IL10A; interleukin-10; T-cell growth inhibitory factor; TGIF
- HostRabbit
- IsotypeIgG
- Protein IDP22301
- Protein NameInterleukin-10
- Scientific DescriptionThe protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]
- ReactivityRat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203