Western blot analysis of extracts from HeLa, HepG2 and HuvEc cells, using IL17RC antibody.
IL17RC Antibody
CSB-PA185992
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetIL17RC
Overview
- SupplierCusabio
- Product NameIL17RC Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID84818
- Target nameIL17RC
- Target descriptioninterleukin 17 receptor C
- Target synonymsCANDF9; IL-17 receptor C; IL17F receptor; IL17Rhom; IL17RL; IL-17RL; IL17-RL; interleukin-17 receptor C; interleukin-17 receptor homolog; interleukin-17 receptor-like protein; zcytoR14
- HostRabbit
- IsotypeIgG
- Protein IDQ8NAC3
- Protein NameInterleukin-17 receptor C
- Scientific DescriptionThis gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling. Gray A.M., Genome Res. 13:2265-2270(2003). Gibbs R.A., Nature 440:1194-1198(2006). Henzel W.J., Protein Sci. 13:2819-2824(2004).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203