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WB analysis of SW480 cell lysate using GTX54364 IL6 Receptor antibody. Dilution : 1:1000 Loading : 25microg per lane
WB analysis of SW480 cell lysate using GTX54364 IL6 Receptor antibody. Dilution : 1:1000 Loading : 25microg per lane
WB analysis of SW480 cell lysate using GTX54364 IL6 Receptor antibody. Dilution : 1:1000 Loading : 25microg per lane

IL6 Receptor antibody

GTX54364
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetIL6R
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Overview

  • Supplier
    GeneTex
  • Product Name
    IL6 Receptor antibody
  • Delivery Days Customer
    7
  • Application Supplier Note
    WB: 1:500 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID3570
  • Target name
    IL6R
  • Target description
    interleukin 6 receptor
  • Target synonyms
    CD126; CD126 antigen; gp80; HIES5; IL-1Ra; IL-6 receptor subunit alpha; IL6Q; IL6QTL; IL-6R; IL-6R-1; IL6RA; IL-6RA; IL6RQ; interleukin-6 receptor subunit alpha; membrane glycoprotein 80
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP08887
  • Protein Name
    Interleukin-6 receptor subunit alpha
  • Scientific Description
    This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.[provided by RefSeq, May 2011]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Targeting prooxidant MnSOD effect inhibits triple-negative breast cancer (TNBC) progression and M2 macrophage functions under the oncogenic stress. Al Haq AT et al., 2022 Jan 11, Cell Death Dis
    Read more
  • Pro-Inflammatory Markers Negatively Regulate IRS1 in Endometrial Cells and Endometrium from Women with Obesity and PCOS. Orostica L et al., 2020 Jan, Reprod Sci
    Read more