iLite® ADCC Target mVEGF (+) Assay Ready Cells can be used for assessing the possibility of an anti-VEGF antibody drug inducing ADCC.
iLite mVEGF (+) Target Assay Ready Cells are based on a human embryonic kidney cell line, HEK2931, and have been genetically engineered and optimized to express high and constant levels of membrane bound VEGF. The cells are to be used as target cells together with iLite® ADCC Effector (V) Assay Ready Cells for measuring the ADCC activity of anti-VEGF antibodies.
* The HEK-293 cell line has been used under a license obtained from AdVec Inc.