iLite® ADCC Target mVEGF (-) Assay Ready Cells can be used for assessing the possibility of an anti-VEGF antibody drug inducing ADCC.
iLite® mVEGF (-) Target Assay Ready Cells are based on a human embryonic kidney cell line, HEK2931, and have been genetically engineered to not express any membrane bound VEGF.
The cells are for use as internal controls together with iLite® ADCC Effector (V) Assay Ready Cells and iLite® mVEGF (+) Target Assay Ready Cells for measuring the ADCC activity of anti-VEGF antibodies.
* The HEK-293 cell line has been used under a license obtained from AdVec Inc.