Western blot analysis of extracts from rat liver cells, using ILK (Ab-246) antibody.
ILK (Ab-246) Antibody
CSB-PA634226
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetILK
Overview
- SupplierCusabio
- Product NameILK (Ab-246) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID3611
- Target nameILK
- Target descriptionintegrin linked kinase
- Target synonyms59 kDa serine/threonine-protein kinase; beta-integrin-linked kinase; epididymis secretory protein Li 28; HEL-S-28; ILK-1; ILK-2; integrin-linked kinase-2; integrin-linked protein kinase; P59; p59ILK
- HostRabbit
- IsotypeIgG
- Protein IDQ13418
- Protein NameIntegrin-linked protein kinase
- Scientific DescriptionReceptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B. Hannigan G.E.,Nature 379:91-96(1996). Janji B.,Oncogene 19:3069-3077(2000). Tadic B.,Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203