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Iminostilbene

HY-N7064
MedChem Express
CAS Number256-96-2
DownloadMSDS
Product group Chemicals
Estimated Purity99.34
Molecular Weight193.249
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Iminostilbene [256-96-2]
  • Delivery Days Customer
    10
  • CAS Number
    256-96-2
  • Certification
    Research Use Only
  • Estimated Purity
    99.34
  • Molecular Formula
    C14H11N
  • Molecular Weight
    193.249
  • Scientific Description
    Iminostilbene is a chemical precursor of carbamazepine. Additionally, Iminostilbene is an orally active inhibitor of PKM2 (Pyruvate Kinase M2) and COX2 (Cyclooxygenase-2). Iminostilbene exerts its effects by inhibiting PKM2 and its interaction with HIF-1alpha and STAT3 , reducing COX2 and iNOS expression, and decreasing LPS-induced release of IL-1beta , IL-6 , TNF-alpha , and MCP-1 , thereby suppressing macrophage-mediated inflammatory responses and improving myocardial ischemia/reperfusion (MI/R) injury. Iminostilbene holds promise for research in inflammation regulation, cardiovascular diseases (such as MI/R injury), and macrophage-mediated immune-related diseases [1] [2] .
  • SMILES
    C12=CC=CC=C1C=CC3=CC=CC=C3N2
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200