IMPDH2-IN-4

MedChem Express

IMPDH2-IN-4

9

Research Use Only

C35H34O6Si

578.73

IMPDH2-IN-4 (compound 2d), a Mycophenolic acid (HY-B0421) analogue, is a selective IMPDH2 inhibitor with a Ki of 1.8 microM. IMPDH2-IN-4 exhibits good cytotoxic activity against osteosarcoma cancer cell lines. IMPDH2-IN-4 possesses a high affinity for VEGFR-2, CDK2, and IMPDH[1].

O=C(O[Si](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)CC/C(C)=C/CC4=C(O)C5=C(COC5=O)C(C)=C4OC

12352200