INCB 3284 dimesylate [887401-93-6]
T11647
CAS Number887401-93-6
Product group Chemicals
Molecular Weight712.76
Overview
- SupplierTargetMol Chemicals
- Product NameINCB 3284 dimesylate
- Delivery Days Customer44
- CAS Number887401-93-6
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameINCB 3284 dimesylate
- Molecular FormulaC28H39F3N4O10S2
- Molecular Weight712.76
- Scientific DescriptionINCB 3284 dimesylate is a selective and orally bioavailable human CCR2 antagonist, inhibiting monocyte chemoattractant protein-1 binding to hCCR2 (IC50: 3.7 nM). It can be used in the research of acute liver failure.
- Shelf life instruction3 years
- SMILESCS(=O)(O)=O.O[C@]1(C2=CN=C(OC)C=C2)CC[C@](N3C[C@@H](CC3)NC(CNC(C4=CC(C(F)(F)F)=CC=C4)=O)=O)([H])CC1.CS(=O)(O)=O
- Storage Instruction-20°C
- UNSPSC12352200
References
- Neuronal CCL2 is upregulated during hepatic encephalopathy and contributes to microglia activation and neurological decline. McMillin M et al., 2014 Jul 10, J NeuroinflammationRead more
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