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INCB3344

HY-50674
MedChem Express
CAS Number1262238-11-8
Product group Chemicals
Estimated Purity98.59
Molecular Weight577.59
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Overview

  • Supplier
    MedChem Express
  • Product Name
    INCB3344 [1262238-11-8]
  • Delivery Days Customer
    10
  • CAS Number
    1262238-11-8
  • Certification
    Research Use Only
  • Estimated Purity
    98.59
  • Molecular Formula
    C29H34F3N3O6
  • Molecular Weight
    577.59
  • Scientific Description
    INCB3344 is a potent, selective and orally bioavailable CCR2 antagonist with IC 50 values of 5.1 nM (hCCR2) and 9.5 nM (mCCR2) in binding antagonism and 3.8 nM (hCCR2) and 7.8 nM (mCCR2) in antagonism of chemotaxis activity.
  • SMILES
    CCO[C@H]1CN([C@]2([H])CC[C@@](CC2)(C3=CC4=C(OCO4)C=C3)O)C[C@@H]1NC(CNC(C5=CC(C(F)(F)F)=CC=C5)=O)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200