More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/Indophagolin

Indophagolin

HY-134807
MedChem Express
CAS Number1207660-00-1
DownloadMSDS
Product group Chemicals
Estimated Purity98.05
Molecular Weight523.75
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    MedChem Express
  • Product Name
    Indophagolin [1207660-00-1]
  • Delivery Days Customer
    10
  • CAS Number
    1207660-00-1
  • Certification
    Research Use Only
  • Estimated Purity
    98.05
  • Molecular Formula
    C19H15BrClF3N2O3S
  • Molecular Weight
    523.75
  • Scientific Description
    Indophagolin is a potent, indoline-containing autophagy inhibitor (IC50=140 nM). Indophagolin antagonizes the purinergic receptor P2X4 as well as P2X1 and P2X3 with IC50s of 2.71, 2.40 and 3.49 microM, respectively. Indophagolin also antagonizes the Gq-protein-coupled P2Y4, P2Y6, and P2Y11 receptors (IC50s =3.4~15.4 microM). Indophagolin has a strong antagonistic effect on serotonin receptor 5-HT6 (IC50=1.0 microM) and a moderate effect on receptors 5-HT1B, 5-HT2B, 5-HT4e, and 5-HT7[1].
  • SMILES
    O=S(C1=CC2=C(C=C1Br)CCN2C(C3CC3)=O)(NC4=CC=C(Cl)C(C(F)(F)F)=C4)=O
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200

Related products

Product group Chemicals
AbMole BioScience
IndophagolinM10546
CAS Number1207660-00-1
Molecular Weight523.75
  • SizePrice
Indophagolin [1207660-00-1]
Product group Chemicals
TargetMol Chemicals
Indophagolin [1207660-00-1]T8946
CAS Number1207660-00-1
Estimated Purity0.9784
Molecular Weight523.75
  • SizePrice
Product group Chemicals
Biorbyt
IndophagolinORB1298503
CAS Number1207660-00-1
Estimated Purity99.76%
Molecular Weight523.75
  • SizePrice