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Sample (50 μg of whole cell lysate) A: mock DF-1 cell lysates B: WSN-infected DF-1 cell lysates 15% SDS PAGE GTX125928 diluted at 1:5000 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
Sample (50 μg of whole cell lysate) A: mock DF-1 cell lysates B: WSN-infected DF-1 cell lysates 15% SDS PAGE GTX125928 diluted at 1:5000 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
Sample (50 μg of whole cell lysate) A: mock DF-1 cell lysates B: WSN-infected DF-1 cell lysates 15% SDS PAGE GTX125928 diluted at 1:5000 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Influenza A virus M1 (matrix protein) antibody

GTX125928
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityVirus
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Overview

  • Supplier
    GeneTex
  • Product Name
    Influenza A virus M1 (matrix protein) antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.76 mg/ml
  • Conjugate
    Unconjugated
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Influenza A virus matrix 1, M1, is a critical protein required for assembly and budding. Hemagglutinin associates with M1 via its cytoplasmic tail and transmembrane domain. The M2 and nucleoprotein proteins are critical in the replication cycle of influenza viruses. The M2 channel protein is an essential component of the viral envelope because of its ability to form a highly selective, pH-regulated, proton-conducting channel. The M2 channel allows protons to enter the interior of the virus and acidification weakens the interaction of the M1 protein with the ribonuclear core.
  • Reactivity
    Virus
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Shi W, Shan Z, Jiang L, et al. ABTB1 facilitates the replication of influenza A virus by counteracting TRIM4-mediated degradation of viral NP protein. Emerg Microbes Infect. 2023,12(2):2270073. doi: 10.1080/22221751.2023.2270073
    Read this paper
  • Chen Y, Wu C, Li H, et al. Antiviral effect and mechanism of Phillyrin and its reformulated FS21 against influenza. Influenza Other Respir Viruses. 2023,17(3):e13112. doi: 10.1111/irv.13112
    Read this paper
  • Chen J, Liu J, Chen Z, et al. Nonmuscle myosin IIA promotes the internalization of influenza A virus and regulates viral polymerase activity through interacting with nucleoprotein in human pulmonary cells. Virol Sin. 2023,38(1):128-141. doi: 10.1016/j.virs.2022.12.002
    Read this paper
  • Hui X, Yu X, Huang K, et al. In vitro and in vivo effects of 3-indoleacetonitrile-A potential new broad-spectrum therapeutic agent for SARS-CoV-2 infection. Antiviral Res. 2023,209:105465. doi: 10.1016/j.antiviral.2022.105465
    Read this paper
  • Li Q, Jiang Z, Ren S, et al. SRSF5-Mediated Alternative Splicing of M Gene is Essential for Influenza A Virus Replication: A Host-Directed Target Against Influenza Virus. Adv Sci (Weinh). 2022,9(34):e2203088. doi: 10.1002/advs.202203088
    Read this paper
  • Bedi S, Mudgal R, Haag A, et al. A Glu-Glu-Tyr Sequence in the Cytoplasmic Tail of the M2 Protein Renders Influenza A Virus Susceptible to Restriction of the Hemagglutinin-M2 Association in Primary Human Macrophages. J Virol. 2022,96(18):e0071622. doi: 10.1128/jvi.00716-22
    Read this paper
  • Xu M, Xia S, Wang M, et al. Enzymatic independent role of sphingosine kinase 2 in regulating the expression of type I interferon during influenza A virus infection. PLoS Pathog. 2022,18(9):e1010794. doi: 10.1371/journal.ppat.1010794
    Read this paper
  • Wang X, Jiang L, Wang G, et al. Influenza A virus use of BinCARD1 to facilitate the binding of viral NP to importin α7 is counteracted by TBK1-p62 axis-mediated autophagy. Cell Mol Immunol. 2022,19(10):1168-1184. doi: 10.1038/s41423-022-00906-w
    Read this paper
  • Zheng H, Ma L, Gui R, et al. G Protein Subunit β1 Facilitates Influenza A Virus Replication by Promoting the Nuclear Import of PB2. J Virol. 2022,96(12):e0049422. doi: 10.1128/jvi.00494-22
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  • Zou J, Yu L, Zhu Y, et al. Transportin-3 Facilitates Uncoating of Influenza A Virus. Int J Mol Sci. 2022,23(8). doi: 10.3390/ijms23084128
    Read this paper