Influenza virus-IN-4

MedChem Express

Influenza virus-IN-4

10

Research Use Only

C23H31FN2O4

418.50

Influenza virus-IN-4 (compound 11e) is a potent influenza virus neuraminidase inhibitor with IC50s of 3.4, 0.094, 0.79, 0.077 microM for H5N1, H5N2, H5N6, H5N8, respectively. Influenza virus-IN-4 shows NA (neuraminidase enzyme)-inhibitory activity. Influenza virus-IN-4 shows low cytotoxicity with an CC50 of >200 microM. Influenza virus-IN-4 shows no obvious toxicity at the dose of 1500 mg/kg in mice[1].

O=C(C1=C[C@@H](OC(CC)CC)[C@H](NC(C)=O)[C@@H](NC/C=C/C2=CC=C(F)C=C2)C1)O

12352200