INHBB Polyclonal Antibody

Reddot Biotech

INHBB Polyclonal Antibody

5

0.8 mg/ml

INHBB

inhibin subunit beta B

activin AB beta polypeptide; activin beta-B chain; inhibin beta B chain; inhibin beta B subunit; Inhibin, beta-2

The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.

-20°C

12352203