INI-43

MedChem Express

INI-43

10

Research Use Only

99.92

C22H23N7

385.46

INI-43 is an inhibitor of Kpnbeta1 , interfering with the nuclear localization of Kpnbeta1 and known Kpnbeta1 cargo proteins, NFAT, NFkappaB, AP-1, and NFY. INI-43 can inhibit the proliferation of cancer cells, cause G 2 -M cell cycle arrest in cancer cells, and induce the intrinsic apoptosis pathway [1] [2] [3] .

NC1=C(C2=NC3=CC=CC=C3N=C2N1CCCN(C)C)C4=NC5=CC=CC=C5N4

-20°C,2°C to 8°C

12352200