Inosine (Standard)

MedChem Express

Inosine (Standard) [58-63-9]

9

Research Use Only

99.93

Inosine (Standard) is the analytical standard of Inosine. This product is intended for research and analytical applications. Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects. Inosine is an agonist for adenosine A 1 ( A 1 R ) and A 2A ( A 2A R ) receptors [1] [2] [3] . In Vitro: Inosine dose-dependently stimulates cAMP production mediated through the A 2A R [2] . Inosine dose-dependently induces hA 2A R-mediated ERK1/2 phosphorylation [2] . Inosine (100 microM; 24 hours) reduces oxidative stress in MES 23.5 cells cultured with astrocytes [3] . In Vivo: Inosine (10-100 mg/kg; i.p.) exhibits antinociceptive effect in mice [2] .

2°C to 8°C

41116135