Insulin antibody [3A6] (Biotin)
GTX40794
Overview
- SupplierGeneTex
- Product NameInsulin antibody [3A6] (Biotin)
- Delivery Days Customer9
- Antibody SpecificityCross-reacts with human proinsulin, bovine insulin (30% ) and porcine insulin. No cross-reaction with free C-peptide.
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID3A6
- Concentration0.70 mg/ml
- ConjugateBiotin
- Gene ID3630
- Target nameINS
- Target descriptioninsulin
- Target synonymsIDDM; IDDM1; IDDM2; ILPR; insulin; IRDN; MODY10; PNDM4; preproinsulin; proinsulin
- HostMouse
- IsotypeIgG1
- Protein IDP01308
- Protein NameInsulin
- Scientific DescriptionAfter removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5 region and with the IGF2 gene at the 3 region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
- ReactivityBovine, Human, Porcine
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Plasma estradiol-17beta, cortisol, and insulin concentrations and serum biochemical parameters surrounding puberty in Japanese Black beef bulls with normal and abnormal semen. Weerakoon WWPN et al., 2020 May, TheriogenologyRead more