![INT-777 [1199796-29-6] INT-777 [1199796-29-6]](https://www.targetmol.com/group3/M00/35/FA/CgoaEWayM4uEDm1iAAAAANJZkas914.png)
INT-777 [1199796-29-6]
T11662L
CAS Number1199796-29-6
Product group Chemicals
Estimated Purity99.89%
Molecular Weight450.65
Overview
- SupplierTargetMol Chemicals
- Product NameINT-777 [1199796-29-6]
- Delivery Days Customer9
- CAS Number1199796-29-6
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameINT-777
- Estimated Purity99.89%
- Molecular FormulaC27H46O5
- Molecular Weight450.65
- Scientific DescriptionINT-777 (S-EMCA) is a potent TGR5 agonist with an EC50 of 0.82 microM. INT-777 (S-EMCA) inhibits NLRP5-ASC inflammasome-mediated neuroinflammation via the TGR3/cAMP/PKA signaling pathway after subarachnoid hemorrhage in rats.
- Shelf life instruction3 years
- SMILES[H][C@@]12CC[C@H]([C@H](C)C[C@H](C)C(O)=O)[C@@]1(C)[C@@H](O)C[C@@]1([H])[C@@]2([H])[C@H](O)[C@H](CC)[C@]2([H])C[C@H](O)CC[C@]12C
- Storage Instruction-20°C
- UNSPSC12352200