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INT-777 [1199796-29-6]

INT-777 [1199796-29-6]

T11662L
TargetMol Chemicals
CAS Number1199796-29-6
Product group Chemicals
Estimated Purity99.89%
Molecular Weight450.65
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    INT-777 [1199796-29-6]
  • Delivery Days Customer
    9
  • CAS Number
    1199796-29-6
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    INT-777
  • Estimated Purity
    99.89%
  • Molecular Formula
    C27H46O5
  • Molecular Weight
    450.65
  • Scientific Description
    INT-777 (S-EMCA) is a potent TGR5 agonist with an EC50 of 0.82 microM. INT-777 (S-EMCA) inhibits NLRP5-ASC inflammasome-mediated neuroinflammation via the TGR3/cAMP/PKA signaling pathway after subarachnoid hemorrhage in rats.
  • Shelf life instruction
    3 years
  • SMILES
    [H][C@@]12CC[C@H]([C@H](C)C[C@H](C)C(O)=O)[C@@]1(C)[C@@H](O)C[C@@]1([H])[C@@]2([H])[C@H](O)[C@H](CC)[C@]2([H])C[C@H](O)CC[C@]12C
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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