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WB analysis of NIH/3T3 cells treated with etoposide 25uM (24h) lysate using GTX86905 Integrin alpha 5 (cleaved Phe42) antibody. The lane on the right is blocked with the synthesized peptide.
WB analysis of NIH/3T3 cells treated with etoposide 25uM (24h) lysate using GTX86905 Integrin alpha 5 (cleaved Phe42) antibody. The lane on the right is blocked with the synthesized peptide.
WB analysis of NIH/3T3 cells treated with etoposide 25uM (24h) lysate using GTX86905 Integrin alpha 5 (cleaved Phe42) antibody. The lane on the right is blocked with the synthesized peptide.

Integrin alpha 5 (cleaved Phe42) antibody

Research Use Only
GTX86905
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse
TargetITGA5
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    Integrin alpha 5 (cleaved Phe42) antibody
  • Delivery Days Customer
    9
  • Antibody Specificity
    Integrin alpha 5 (cleaved Phe42) antibody detects endogenous levels of fragment of activated ITGA5 resulting from cleavage adjacent to Phe42.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID3678
  • Target name
    ITGA5
  • Target description
    integrin subunit alpha 5
  • Target synonyms
    CD49 antigen-like family member E; CD49e; fibronectin receptor subunit alpha; fibronectin receptor, alpha polypeptide; fibronectin receptor, alpha subunit; FNRA; integrin alpha-5; integrin alpha-F; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); ITGA5/SLC9B1 fusion; very late activation protein 5, alpha subunit; VLA-5; VLA5A
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. Integrin alpha 5 and integrin alpha V chains are produced by distinct genes. [provided by RefSeq, Jan 2015]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203

References

  • Piezo1 and Gq/G11 promote endothelial inflammation depending on flow pattern and integrin activation. Albarran-Juarez J et al., 2018 Oct 1, J Exp Med
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