WB analysis of NIH/3T3 cells treated with etoposide 25uM (24h) lysate using GTX86905 Integrin alpha 5 (cleaved Phe42) antibody. The lane on the right is blocked with the synthesized peptide.
Integrin alpha 5 (cleaved Phe42) antibody
GTX86905
Overview
- SupplierGeneTex
- Product NameIntegrin alpha 5 (cleaved Phe42) antibody
- Delivery Days Customer9
- Antibody SpecificityIntegrin alpha 5 (cleaved Phe42) antibody detects endogenous levels of fragment of activated ITGA5 resulting from cleavage adjacent to Phe42.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID3678
- Target nameITGA5
- Target descriptionintegrin subunit alpha 5
- Target synonymsCD49 antigen-like family member E; CD49e; fibronectin receptor subunit alpha; fibronectin receptor, alpha polypeptide; fibronectin receptor, alpha subunit; FNRA; integrin alpha-5; integrin alpha-F; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); ITGA5/SLC9B1 fusion; very late activation protein 5, alpha subunit; VLA-5; VLA5A
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. Integrin alpha 5 and integrin alpha V chains are produced by distinct genes. [provided by RefSeq, Jan 2015]
- ReactivityHuman, Mouse
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203
References
- Piezo1 and Gq/G11 promote endothelial inflammation depending on flow pattern and integrin activation. Albarran-Juarez J et al., 2018 Oct 1, J Exp MedRead more