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WB analysis of NIH/3T3 cells treated with etoposide 25uM (24h) lysate using GTX86905 Integrin alpha 5 (cleaved Phe42) antibody. The lane on the right is blocked with the synthesized peptide.
WB analysis of NIH/3T3 cells treated with etoposide 25uM (24h) lysate using GTX86905 Integrin alpha 5 (cleaved Phe42) antibody. The lane on the right is blocked with the synthesized peptide.
WB analysis of NIH/3T3 cells treated with etoposide 25uM (24h) lysate using GTX86905 Integrin alpha 5 (cleaved Phe42) antibody. The lane on the right is blocked with the synthesized peptide.

Integrin alpha 5 (cleaved Phe42) antibody

GTX86905
GeneTex
TargetITGA5
Product group Antibodies
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Overview

  • Supplier
    GeneTex
  • Product Name
    Integrin alpha 5 (cleaved Phe42) antibody
  • Delivery Days Customer
    9
  • Antibody Specificity
    Integrin alpha 5 (cleaved Phe42) antibody detects endogenous levels of fragment of activated ITGA5 resulting from cleavage adjacent to Phe42.
  • Application Supplier Note
    WB: 1:500~1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Formulation
    Liquid
  • Gene ID3678
  • Target name
    ITGA5
  • Target description
    integrin subunit alpha 5
  • Target synonyms
    CD49 antigen-like family member E; CD49e; fibronectin receptor subunit alpha; fibronectin receptor, alpha polypeptide; fibronectin receptor, alpha subunit; FNRA; integrin alpha-5; integrin alpha-F; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); ITGA5/SLC9B1 fusion; very late activation protein 5, alpha subunit; VLA-5; VLA5A
  • Protein IDP08648
  • Protein Name
    Integrin alpha-5
  • Scientific Description
    The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. Integrin alpha 5 and integrin alpha V chains are produced by distinct genes. [provided by RefSeq, Jan 2015]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Piezo1 and Gq/G11 promote endothelial inflammation depending on flow pattern and integrin activation. Albarran-Juarez J et al., 2018 Oct 1, J Exp Med
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