Interferon alpha-2 (IFNA2)(N39), CF405S conjugate, 0.1mg/mL [26628-22-8]
BNC040298
ReactivityBovine, Human, Mouse
Product group Antibodies
TargetIFNA2
Overview
- SupplierBiotium
- Product NameInterferon alpha-2 (IFNA2)(N39), CF405S conjugate, 0.1mg/mL
- Delivery Days Customer9
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDN39
- Concentration0.1 mg/ml
- ConjugateOther Conjugate
- Gene ID3440
- Target nameIFNA2
- Target descriptioninterferon alpha 2
- Target synonymsalpha-2a interferon; IFNA; IFNA2B; IFN-alpha-2; IFN-alphaA; interferon alpha 2a; interferon alpha 2b; interferon alpha A; interferon alpha-2; leIF A
- HostMouse
- IsotypeIgG1
- Protein IDP01563
- Protein NameInterferon alpha-2
- Scientific DescriptionThis antibody recognizes a protein of 16-27 kDa, identified as human interferon-alpha-2 (IFN-a2). Its epitope maps between aa112-148 of IFN-a2 (total aa172). This MAb is specific for IFN-a2 and does not cross-react with interferon-alpha-1. The site recognized by this MAb is called site I and is responsible for the antiviral and anti-proliferative activities of IFN-a2. Epitopes of N27 and N39 MAbs are different and represent a good combination of antibodies to set up an ELISA assay for the quantitation of IFN-a2 after viral infections. The IFN-a family consists of 24 or more genes or pseudo-genes. IFN-a2 is one of the two distinct families (I and II) of human IFN-a. The alpha-interferons are mainly produced by lymphocytes, monocytes, macrophages, and cell lines such as Namalwa and KG1 following induction by viruses, nucleic acids, and glucocorticoid hormones. They are involved in virus resistance on target cells, inhibition of cell proliferation, induction of cytokines and regulation of expression of MHC class I antigens.
- SourceAnimal
- ReactivityBovine, Human, Mouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203