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InVivoMAb anti-mouse CD47 (IAP)

Research Use Only
BE0270
Bio X Cell
ApplicationsImmunoFluorescence, Neutralisation/Blocking
Product group Antibodies
ReactivityMouse
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Overview

  • Supplier
    Bio X Cell
  • Product Name
    InVivoMAb anti-mouse CD47 (IAP)
  • Delivery Days Customer
    7
  • Applications
    ImmunoFluorescence, Neutralisation/Blocking
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    MIAP301
  • Concentration
    4-11 mg/ml
  • Estimated Purity
    >95%
  • Host
    Rat
  • Isotype
    IgG2a
  • Reactivity
    Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Single-cell RNA sequencing reveals compartmental remodeling of tumor-infiltrating immune cells induced by anti-CD47 targeting in pancreatic cancer. Pan Y et al., 2019 Nov 27, J Hematol Oncol
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  • Epithelial CD47 is critical for mucosal repair in the murine intestine in vivo. Reed M et al., 2019 Nov 1, Nat Commun
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  • Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47-mediated dont-eat-me signal. Liu M et al., 2019 Jan 21, Nat Immunol
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  • Enhancing immunotherapy of STING agonist for lymphoma in preclinical models. Sallets A et al., 2018 Sep 11, Blood Adv
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  • Anti-CD47 treatment enhances anti-tumor T-cell immunity and improves immunosuppressive environment in head and neck squamous cell carcinoma. Wu L et al., 2018, Oncoimmunology
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  • Dendritic Cells but Not Macrophages Sense Tumor Mitochondrial DNA for Cross-priming through Signal Regulatory Protein alpha Signaling. Xu MM et al., 2017 Aug 15, Immunity
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  • Engineering high-affinity PD-1 variants for optimized immunotherapy and immuno-PET imaging. Maute RL et al., 2015 Nov 24, Proc Natl Acad Sci U S A
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  • CD47 blockade triggers T cell-mediated destruction of immunogenic tumors. Liu X et al., 2015 Oct, Nat Med
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  • CD47 deficiency ameliorates autoimmune nephritis in Fas(lpr) mice by suppressing IgG autoantibody production. Shi L et al., 2015 Nov, J Pathol
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  • Deficits in cerebellar granule cell development and social interactions in CD47 knockout mice. Hsieh CP et al., 2015 May, Dev Neurobiol
    Read more

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