InVivoMAb anti-mouse OX40 (CD134)

Unique potential of 4-1BB agonist antibody to promote durable regression of HPV+ tumors when combined with an E6/E7 peptide vaccine. Bartkowiak T et al., 2015 Sep 22, Proc Natl Acad Sci U S A

PD-1 Co-inhibitory and OX40 Co-stimulatory Crosstalk Regulates Helper T Cell Differentiation and Anti-Plasmodium Humoral Immunity. Zander RA et al., 2015 May 13, Cell Host Microbe

Three steps to breaking immune tolerance to lymphoma: a microparticle approach. Makkouk A et al., 2015 Apr, Cancer Immunol Res

Combined targeting of costimulatory (OX40) and coinhibitory (CTLA-4) pathways elicits potent effector T cells capable of driving robust antitumor immunity. Redmond WL et al., 2014 Feb, Cancer Immunol Res

PD-1 blockade and OX40 triggering synergistically protects against tumor growth in a murine model of ovarian cancer. Guo Z et al., 2014, PLoS One

Central memory CD8+ T lymphocytes mediate lung allograft acceptance. Krupnick AS et al., 2014 Mar, J Clin Invest

Regulatory CD8+ T cells associated with erosion of immune surveillance in persistent virus infection suppress in vitro and have a reversible proliferative defect. Hu Z et al., 2013 Jul 1, J Immunol

Type I IFN-dependent T cell activation is mediated by IFN-dependent dendritic cell OX40 ligand expression and is independent of T cell IFNR expression. Kurche JS et al., 2012 Jan 15, J Immunol

New insights on OX40 in the control of T cell immunity and immune tolerance in vivo. Xiao X et al., 2012 Jan 15, J Immunol

NF-kappaB-inducing kinase plays an essential T cell-intrinsic role in graft-versus-host disease and lethal autoimmunity in mice. Murray SE et al., 2011 Dec, J Clin Invest