IPO4 Polyclonal Antibody
RD266496A
ApplicationsImmunoFluorescence
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetIPO4
Overview
- SupplierReddot Biotech
- Product NameIPO4 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoFluorescence
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID79711
- Target nameIPO4
- Target descriptionimportin 4
- Target synonymsImp4; imp4b; importin-4; importin-4b; ran-binding protein 4; ranBP4
- HostRabbit
- IsotypeIgG
- Scientific DescriptionImportin-4is aproteinthat in humans is encoded by theIPO4gene. Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203