IQSEC2 antibody

GeneTex

IQSEC2 antibody

9

At least two isoforms of IQSEC2 are known to exist; this antibody will only detect the larger isoform. IQSEC2 antibody is predicted to not cross-react with IQSEC1.

WB: 1 - 2 microg/mL. IHC-P: 5 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

IQSEC2

IQ motif and Sec7 domain ArfGEF 2

BRAG1; brefeldin A resistant Arf-guanine nucleotide exchange factor 1; brefeldin A resistant Arf-guanine nucleotide exchange factor 1b; brefeldin A resistant Arf-guanine nucleotide exchange factor 1c; IQ motif and Sec7 domain 2; IQ motif and SEC7 domain-containing protein 2; IQ-ArfGEF; mental retardation, X-linked 18; MRX1; MRX18; MRX78; XLID1

Rabbit

IgG

IQ motif and SEC7 domain-containing protein 2

This gene encodes a guanine nucleotide exchange factor for the ARF family of small GTP-binding proteins. The encoded protein is a component of the postsynaptic density at excitatory synapses, and may play a critical role in cytoskeletal and synaptic organization through the activation of selected ARF substrates including ARF1 and ARF6. Mutations in this gene have been implicated in nonsyndromic X-linked mental retardation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203