Bio-Connect

Zomiradomide

HY-153368
MedChem Express
Estimated Purity95.43
Product group Chemicals
Molecular Weight871.97
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Overview

  • Supplier
    MedChem Express
  • Product Name
    IRAK degrader-1
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Estimated Purity
    95.43
  • Molecular Formula
    C45H48F3N7O6S
  • Molecular Weight
    871.97
  • Scientific Description
    KT-413 (example I-3) is an orally active PROTAC-class IRAK degrader [1] . KT-413 consists of a target protein ligand (red part) PROTAC IRAK4 ligand-5 (HY-168311), an E3 ubiquitin ligase ligand (blue part) Thalidomide-4-Br (HY-W039116), and a PROTAC linker (black part) 2-(2-Azaspiro[3.3]heptan-6-yl)ethanamine (HY-168313). E3 ubiquitin ligase and linker can form Thalidomide-NH-C2-2-azaspiro[3.3]heptane (HY-168312). The active control for the target protein ligand is RSL3-4-Me (HY-169375).
  • SMILES
    O=C(N1C2C(NC(CC2)=O)=O)C3=CC=CC(NCCC(C4)CC4(C5)CN5C[C@H]6CC[C@H](C(SC7=C8)=NC7=CC(C(C)(O)C)=C8NC(C9=CC=CC(C(F)(F)F)=N9)=O)CC6)=C3C1=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200