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IRAK4-IN-18

Research Use Only
HY-150732
MedChem Express
Molecular Weight464.49
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Product group Chemicals

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Overview

  • Supplier
    MedChem Express
  • Product Name
    IRAK4-IN-18
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Molecular Formula
    C24H25FN6O3
  • Molecular Weight
    464.49
  • Scientific Description
    IRAK4-IN-18 is a potent interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor with an IC50 value of 15 nM. IRAK4-IN-18 can inhibit LPS-induced IL23 production in THP and DC cells, and stop arthritis development in arthritis rats. IRAK4-IN-18 can be used for researching arthritis disease[1].
  • SMILES
    O=C(N)[C@@H]1C([C@@H]2C[C@H]1C=C2)NC3=NC(NC4=CC(N5CCOCC5)=CC(F)=C4)=NC6=C3OC=C6
  • UNSPSC
    12352200