IRAK4-IN-19

MedChem Express

IRAK4-IN-19

10

Research Use Only

C25H26F2N8O

492.52

IRAK4-IN-19 is a potent interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor with an IC50 value of 4.3 nM. IRAK4-IN-19 can inhibit LPS-induced IL23 production in THP and DC cells, and stop arthritis development in arthritis rats. IRAK4-IN-19 can be used for researching arthritis disease.

CC(N1N=CC2=C1C=C(NC(N=C3C=C4)=NC(N[C@H]5[C@@H](C(N)=O)[C@@H]6C=C[C@H]5C6)=C3N4C(F)F)C=C2)C

See Manual

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