Western Blot analysis of Jurkat cell using IRF4 Polyclonal Antibody at dilution of 1:400
IRF4 Polyclonal Antibody
E-AB-13342
Product group Antibodies
Overview
- SupplierElabscience
- Product NameIRF4 Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA WB
- CertificationResearch Use Only
- Concentration0.2mg/ml
- Scientific DescriptionThe protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.
- UNSPSC12352203